Recent research into the anatomy and pathophysiology of the blood brain and blood spinal cord barriers suggests that a breakdown in these barriers can result in several diseases affecting the central nervous system cns. Interaction of circulating leukocytes with the endothelium of the blood spinal cord and blood brain barrier therefore is a critical step in the pathogenesis of inflammatory diseases of the cns leukocyte endothelial interactions are mediated by adhesion molecules and chemokines and their respective chemokine receptors. Blood spinal cord and brain barriers in health and disease document for blood spinal cord and brain barriers in health and disease is available in various format such as pdf doc and epub which you can. Lets talk about the blood brain barrier the bbb or as it is sometimes called the blood brain spinal cord barrier as you may recall from biology 101 this is the physical structure a kind of wall that separates blood and the cerebrospinal fluid that surrounds the brain and spinal cord. The blood brain barrier shown that when a person is undergoing an ms attack the blood brain barrier has broken down in a section of the brain or spinal cord allowing white blood cells called t lymphocytes to cross over and attack the rather than being a disease of the immune system ms is a disease of the blood brain barrier
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